In I Feel Sick, it's revealed that she has remained somewhat socially reclusive ever since her disastrous first date. Her later attempts at dating fared no better, and have in fact become worse (her last two attempts being a sufferer of irritable bowel syndrome (IBS) and the homicidal maniac himself). Presently, she has become even more of a shut-in and has been attempting to make money as a professional artist. However, she finds the job both monotonous and annoying. Also, Dev i can't seem to create practically anything for herself. Her latest creation was that of Sickness, a painting of a doll-like version of herself who is able to talk to her (much like the Doughboys in JTHM). Devi fears that Sickness is stealing her creativity, which is proven to be true when Sickness keeps telling her to ignore her/let her take over (and that there is no way to stop her), and when Devi recalls a conversation she had with Johnny about what happens when a person's most defining trait is taken away from them (it is implied that Johnny is the one that caused Devi's current mental state and that she will become like Johnny if she allows Sickness to continue taking from her). She quits her job at Nerve Publishing, and rushes home to try and beat Sickness. However, Sickness laid several traps for Devi along the way (her friend Tenna, dead animals, a perverted man, a hyperactive child, and the Psychic Fat Lady). She attempts to squeeze through the Psychic Fat Lady's fat and learns that it's what makes the lady psychic. It tells Devi about a boy she used to know as a child named Spidgey Simmons. He was in love with her but she didn't seem to accept/grasp these feelings and rejected him. He later died of a chalk-induced asthma attack, caused by Devi breathing chalk dust into his face (accidentally). Because of this, Devi can never have a good relationship and she must keep her creativity or she will lose herself altogether. She makes it home, only to find Sickness has escaped the painting (albeit prematurely). Sickness makes one last effort to convince Devi to give up, but Devi declines and states that her life sucks. However, she must keep it because it's all that Devi has (and that Sickness is now her tortured audience).